Sunlight, dietary habits, genetic polymorphisms and vitamin D deficiency in urban and rural infants of Bangladesh.

ABSTRACT: We conducted an observational study to assess the prevalence and risk factors of vitamin D deficiency in 12-24 months old children living in urban and rural Bangladesh. Serum 25-hydroxyvitamin D (free 25(OH)D) level, socio-demographic status, anthropometric status, dietary intake, exposure to sunlight and single nucleotide polymorphisms in vitamin-D pathway genes were measured in 208 children. Vitamin D deficiency (free 25(OH)D < 50 nmol/l) was reported in 47% of the children. Multivariable logistic regression model identified duration to sunlight exposure (regression coefficient, β =  - 0.01; 95% CI 0.00, - 0.02; p-value < 0.05), UV index (β =  - 0.36; 95% CI 0.00, - 0.02; p-value < 0.05) and breast-feeding (β =  - 1.15; 95% CI - 0.43, - 1.86; p-value < 0.05) to be negatively associated w

SUBMITTER: Das S 

PROVIDER: S-EPMC8901932 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature