Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry.

ABSTRACT:

Background

The accumulation of risk for the development of rheumatoid arthritis (RA) is regarded as a continuum that may start with interacting environmental and genetic factors, proceed with the initiation of autoimmunity, and result in the formation of autoantibodies such as anti-citrullinated peptide antibodies (ACPA). In parallel, at-risk individuals may be asymptomatic or experience joint pain (arthralgia) that is itself non-specific or clinically suspicious for evolving RA, even in the absence of overt arthritis. Optimal strategies for the management of people at-risk of RA, both for symptom control and to delay or prevent progression to classifiable disease, remain poorly understood.

Methods

To help address this, groups of stakeholders from academia, clinical rheumato

SUBMITTER: Studenic P 

PROVIDER: S-EPMC8901993 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature