Association of Body Mass Index With Clinical Outcomes in Patients With Cystic Fibrosis: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

The prevalence of overweight (body mass index [BMI] = 25-29.9 [calculated as weight in kilograms divided by height in meters squared]) and obesity (BMI ≥30) is increasing among patients with cystic fibrosis (CF). However, it is unclear whether there is a benefit associated with increasing weight compared with the reference range (ie, normal) in CF.

Objective

To evaluate the association of altered BMI or body composition and clinical outcomes in patients with CF.

Data sources

For this systematic review and meta-analysis, the literature search was conducted November 2, 2020, of 3 databases: MEDLINE (via PubMed), Embase, and Cochrane Central Register of Controlled Trials.

Study selection

Patients older than 2 years diagnosed with CF with altered body co

SUBMITTER: Nagy R 

PROVIDER: S-EPMC8902650 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature