Exposure to ambient air pollution and early childhood behavior: A longitudinal cohort study.

ABSTRACT:

Background

Prenatal and early life air pollution exposure may impair healthy neurodevelopment, increasing risk of childhood behavioral disorders, but epidemiological evidence is inconsistent. Little is known about factors that determine susceptibility.

Methods

Participants were mother-child dyads from the CANDLE study, an ECHO PATHWAYS Consortium birth cohort set in the mid-South United States, who completed a preschool visit. We estimated prenatal and childhood exposures to nitrogen dioxide (NO₂) and particulate matter less than 10 μm (PM₁₀) at participants' residences using a national annual average universal kriging model (land-use regression with spatial smoothing). Distance to nearest major roadway was used as a proxy for traffic-related pollution.

SUBMITTER: Loftus CT 

PROVIDER: S-EPMC8903039 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature