Changes in mood and health-related quality of life in Look AHEAD 6 years after termination of the lifestyle intervention.

ABSTRACT:

Objective

The Action for Health in Diabetes (Look AHEAD) study previously reported that intensive lifestyle intervention (ILI) reduced incident depressive symptoms and improved health-related quality of life (HRQOL) over nearly 10 years of intervention compared with a control group (the diabetes support and education group [DSE]) in participants with type 2 diabetes and overweight or obesity. The present study compared incident depressive symptoms and changes in HRQOL in these groups for an additional 6 years following termination of the ILI in September 2012.

Methods

A total of 1,945 ILI participants and 1,900 DSE participants completed at least one of four planned postintervention assessments at which weight, mood (via the Patient Health Questionnaire-9), antidepressant me

SUBMITTER: Look AHEAD Research Group 

PROVIDER: S-EPMC8903054 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature