Cardiovascular risk factor progression in adolescents and young adults with youth-onset type 2 diabetes.

ABSTRACT:

Aims

Youth-onset type 2 diabetes (T2D) confers a high risk of early adverse cardiovascular morbidity. We describe the cumulative incidence and prevalence of cardiovascular risk factors over time and examine relationships with diabetes progression in young adults with youth-onset T2D from the Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) study.

Methods

Longitudinal data was used to evaluate the relationships between hypertension, LDL-C dyslipidemia, hypertriglyceridemia, and smoking with risk factors in 677 participants.

Results

Baseline mean age was 14 ± 2 years and mean follow-up 10.2 ± 4.5 years. The 14-year cumulative incidence of hypertension, LDL-C dyslipidemia, and hypertriglyceridemia was 59%, 33%, and 37% respectively. Average prevalen

SUBMITTER: TODAY Study Group 

PROVIDER: S-EPMC8903081 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature