International consensus to standardise histopathological scoring for small bowel strictures in Crohn's disease.

ABSTRACT:

Objective

Effective medical therapy and validated trial outcomes are lacking for small bowel Crohn's disease (CD) strictures. Histopathology of surgically resected specimens is the gold standard for correlation with imaging techniques. However, no validated histopathological scoring systems are currently available for small bowel stricturing disease. We convened an expert panel to evaluate the appropriateness of histopathology scoring systems and items generated based on panel opinion.

Design

Modified RAND/University of California Los Angeles methodology was used to determine the appropriateness of 313 candidate items related to assessment of CD small bowel strictures.

Results

In this exercise, diagnosis of naïve and anastomotic strictures required increased bowel wal

SUBMITTER: Gordon IO 

PROVIDER: S-EPMC8903083 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature