Improving neurodevelopment in Zika-exposed children: A randomized controlled trial.

ABSTRACT:

Background

While microcephaly is a significant adverse outcome of prenatal exposure to the Zika virus (ZIKV), subtle malformations of cortical development (MCD) have been observed in Zika-exposed children (ZEC), including delays in language, cognition, and motor domains, and visual acuity deficits. Interventions within the first 1,000 days of life can significantly improve developmental outcomes. This study examined a 12-week Responsive Caregiving Intervention on neurodevelopmental outcomes in 24-30-month-old ZEC.

Methodology/principal findings

A randomized controlled trial was implemented in Grenada, West Indies using an existing ZIKV cohort surveillance study. When children in that study turned 24 months, baseline child neurodevelopmental measures and caregiver interviews

SUBMITTER: Waechter R 

PROVIDER: S-EPMC8903297 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature