Safety of the BNT162b2 mRNA COVID-19 vaccine in patients with familial Mediterranean fever.

ABSTRACT:

Objectives

Evidence suggests a possible association between the COVID-19 vaccine and autoimmune disease flares or new onset of various autoinflammatory manifestations, such as pericarditis and myocarditis. The objective of this study was to assess the safety of an mRNA-based BNT162b2 anti-COVID-19 vaccine in individuals with FMF, a prototypic autoinflammatory disease.

Methods

Patients participating in this study fulfilled the criteria for diagnosis of FMF, were older than 18 years and received at least one dose of the vaccine. Data on baseline characteristics, features of FMF, post-vaccination side effects, and disease flares were acquired using electronic medical files and telephone interviews.

Results

A total of 273 FMF patients were recruited for the study. >95% we

SUBMITTER: Shechtman L 

PROVIDER: S-EPMC8903441 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature