Gut microbiota in patients with obesity and metabolic disorders - a systematic review.

ABSTRACT:

Background

Previous observational studies have demonstrated inconsistent and inconclusive results of changes in the intestinal microbiota in patients with obesity and metabolic disorders. We performed a systematic review to explore evidence for this association across different geography and populations.

Methods

We performed a systematic search of MEDLINE (OvidSP) and Embase (OvidSP) of articles published from Sept 1, 2010, to July 10, 2021, for case-control studies comparing intestinal microbiome of individuals with obesity and metabolic disorders with the microbiome of non-obese, metabolically healthy individuals (controls). The primary outcome was bacterial taxonomic changes in patients with obesity and metabolic disorders as compared to controls. Taxa were defined as "le

SUBMITTER: Xu Z 

PROVIDER: S-EPMC8903526 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature