Childhood infections and autism spectrum disorders and/or intellectual disability: a register-based cohort study.

ABSTRACT:

Objective

To explore the associations between childhood infections and subsequent diagnoses of autism spectrum disorder (ASD), intellectual disability (ID), and their co-occurrence.

Methods

The association between specialized care for any infection, defined by ICD-codes, and later ASD or ID was investigated in a register-based cohort of 556,732 individuals born 1987-2010, resident in Stockholm County, followed from birth to their 18th birthday or December 31, 2016. We considered as potential confounders children's characteristics, family socioeconomic factors, obstetric complications, and parental histories of treatment for infection and psychiatric disorders in survival analyses with extended Cox regression models. Residual confounding by shared familial factors was address

SUBMITTER: Karlsson H 

PROVIDER: S-EPMC8903600 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature