Effect of pelvic laparoscopic implantation of neuroprosthesis in spinal cord injured subjects: a 1-year prospective randomized controlled study.

ABSTRACT:

Study design

1-year prospective RCT.

Objective

Examine the effect of implantable pulse generator and low-frequency stimulation of the pelvic nerves using laparoscopic implantation of neuroprosthesis (LION) compared with neuromuscular electrical stimulation (NMES) in SCI.

Methods

Inclusion criteria: traumatic spinal cord injury (SCI), age 18-55 years, neurological level-of-injury Th4-L1, time-since-injury >1 year, and AIS-grades A-B. Participants were randomized to (A) LION procedure or (B) control group receiving NMES.

Primary outcome measure

Walking Index for Spinal Cord Injury (WISCI-II), which is a SCI specific outcome measure assessing ability to ambulate.

Secondary outcome measures

Spinal Cord Independence Measure III (SCIM III), Patient Global Impr

SUBMITTER: Kasch H 

PROVIDER: S-EPMC8904257 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature