Prognostic significance of serum tumor marker normalization in the perioperative period for patients with advanced gastric cancer.

ABSTRACT:

Background

Neoadjuvant chemotherapy (NCT) was developed to improve the prognosis of patients with advanced gastric cancer (AGC). Some studies have confirmed the diagnostic and prognostic value of various serum tumor markers in gastric cancer. However, most of these studies were focused on the value of preoperative and postoperative tumor markers in patients undergoing surgery with or without adjuvant therapy, and only a few studies focused on AGC patients undergoing NCT.

Methods

We retrospectively analyzed the data of consecutive patients with histologically confirmed AGC who received NCT prior to surgical resection at Zhejiang Cancer Hospital from January 2010 to September 2018. The prognostic impact of tumor markers before and after NCT, including Carcinoembryonic antigen

SUBMITTER: Hu C 

PROVIDER: S-EPMC8904975 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature