Predictive Accuracy of a Perioperative Laboratory Test-Based Prediction Model for Moderate to Severe Acute Kidney Injury After Cardiac Surgery.

ABSTRACT:

Importance

Effective treatment of acute kidney injury (AKI) is predicated on timely diagnosis; however, the lag in the increase in serum creatinine levels after kidney injury may delay therapy initiation.

Objective

To determine the derivation and validation of predictive models for AKI after cardiac surgery.

Design, setting, and participants

Multivariable prediction models were derived based on a retrospective observational cohort of adult patients undergoing cardiac surgery between January 2000 and December 2019 from a US academic medical center (n = 58 526) and subsequently validated on an external cohort from 3 US community hospitals (n = 4734). The date of final follow-up was January 15, 2020.

Exposures

Perioperative change in serum creatinine and postopera

SUBMITTER: Demirjian S 

PROVIDER: S-EPMC8905398 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature