Exploring the associations between polypharmacy and COVID-19-related hospitalisations and deaths: a population-based cohort study among older adults in Quebec, Canada.

ABSTRACT:

Objectives

To study the association between polypharmacy and the risk of hospitalisation and death in cases of COVID-19 in the population over the age of 65.

Design

Population-based cohort study.

Setting

Quebec Integrated Chronic Disease Surveillance System, composed of five medico-administrative databases, in the province of Quebec, Canada.

Participants

32 476 COVID-19 cases aged over 65 whose diagnosis was made between 23 February 2020 and 15 March 2021, and who were covered by the public drug insurance plan (thus excluding those living in long-term care). We counted the number of different medications they claimed between 1 April 2019 and 31 March 2020.

Outcome measures

Robust Poisson regression was used to calculate relative risk of hospitalisation a

SUBMITTER: Sirois C 

PROVIDER: S-EPMC8905411 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature