Glycemic variability assessed by continuous glucose monitoring in hospitalized patients with community-acquired pneumonia.

ABSTRACT:

Background

Glycemic variability (GV) has only been sparsely studied in patients with community-acquired pneumonia (CAP). This study aimed to quantify in-hospital GV in CAP patients, including determining the impact of type 2 diabetes mellitus (T2DM) and glucocorticoid (GC) treatment on GV.

Methods

This is a prospective cohort study of CAP patients (N = 40) with or without T2DM and treated or not with GCs. The primary endpoint was GV measured as glucose standard deviation (SD), coefficient of variation (CV), and postprandial glucose excursions (PPGE) based on continuous glucose monitoring (CGM). Analysis of glucose data was split into daytime and nighttime when possible.

Results

Patients included had a mean age of 74 (range 55 to 91) years. SD (95%CI) increased by a fa

SUBMITTER: Olsen MT 

PROVIDER: S-EPMC8905566 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature