Chorioamnionitis and Risk for Maternal and Neonatal Sepsis: A Systematic Review and Meta-analysis.

ABSTRACT:

Objective

To estimate the risk of maternal and neonatal sepsis associated with chorioamnionitis.

Data sources

PubMed, BIOSIS, and ClinicalTrials.gov databases were systematically searched for full-text articles in English from inception until May 11, 2020.

Methods of study selection

We screened 1,251 studies. Randomized controlled trials, case-control, or cohort studies quantifying a relationship between chorioamnionitis and sepsis in mothers (postpartum) or neonates born at greater than 22 weeks of gestation were eligible. Studies were grouped for meta-analyses according to exposures of histologic or clinical chorioamnionitis and outcomes of maternal or neonatal sepsis.

Tabulation, integration, and results

One hundred three studies were included, and 55 met cr

SUBMITTER: Beck C 

PROVIDER: S-EPMC8905581 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature