Tailoring conductive inverse opal films with anisotropic elliptical porous patterns for nerve cell orientation.

ABSTRACT:

Background

The nervous system is critical to the operation of various organs and systems, while novel methods with designable neural induction remain to exploit.

Results

Here, we present a conductive inverse opal film with anisotropic elliptical porous patterns for nerve orientation induction. The films are fabricated based on polystyrene (PS) inverse opal scaffolds with periodical elliptical porous structure and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) mixed polyacrylamide (PAAm) polymers fillers. It is demonstrated that the anisotropic elliptical surface topography allows the nerve cells to be induced into orientation connected with the stretching direction. Because of the anisotropic features of the film which can be stretched into different dir

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC8905848 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature