Target margin design through analyzing a large cohort of clinical log data in the cyberknife system.

ABSTRACT:

Purpose

Calculating the adequate target margin for real-time tumor tracking using the Cyberknife system is a challenging issue since different sources of error exist. In this study, the clinical log data of the Cyberknife system were analyzed to adequately quantify the planned target volume (PTV) margins of tumors located in the lung and abdomen regions.

Methods

In this study, 45 patients treated with the Cyberknife module were examined. In this context, adequate PTV margins were estimated based on the Van Herk formulation and the uncertainty estimation method by considering the impact of errors and uncertainties. To investigate the impact of errors and uncertainties on the estimated PTV margins, a statistical analysis was also performed.

Results

Our study demonstrate

SUBMITTER: Samadi Miandoab P 

PROVIDER: S-EPMC8906228 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature