The psychoactive effects of Bryophyllum pinnatum (Lam.) Oken leaves in young zebrafish.

ABSTRACT: Bryophyllum pinnatum (Lam.) Oken (BP) is a plant that is used worldwide to treat inflammation, infections, anxiety, restlessness, and sleep disorders. While it is known that BP leaves are rich in flavonoids, the extent of the beneficial and toxic effects of its crude extracts remains unclear. Although some neurobehavioral studies using leaf extracts have been conducted, none has examined the effects of water-extracted leaf samples. The zebrafish is a powerful animal model used to gain insights into the efficacy and toxicity profiles of this plant due to its high fecundity, external development, and ease of performing behavioral assays. In this study, we performed behavioral testing after acute exposure to different concentrations of aqueous extract from leaves of B. pinnatum (LABP) on larv

SUBMITTER: Martins Fernandes Pereira K 

PROVIDER: S-EPMC8906576 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature