Predictors and Mortality for Worsening Left Ventricular Ejection Fraction in Patients With HFpEF.

ABSTRACT:

Background

Definitions of declined left ventricular ejection fraction (LVEF) vary across studies and research results concerning the association of mortality with declined LVEF are inconsistent. Thus, this study aimed to assess the impact of early worsening LVEF on mortality in patients with heart failure (HF) with preserved ejection fraction (HFpEF) and to establish independent predictors of early worsening LVEF.

Methods and results

A total of 1,418 consecutive patients with HFpEF with LVEF remeasurement from the Cardiorenal Improvement registry were included in this study. Worsening LVEF was defined as an absolute decline ≥ 5% from baseline LVEF within 3 to 12 months after discharge. The Cox and logistic regression analyses were performed to assess prognostic effects and p

SUBMITTER: Chen L 

PROVIDER: S-EPMC8907533 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature