Comparison of Seroconversion in Children and Adults With Mild COVID-19.

ABSTRACT:

Importance

The immune response in children with SARS-CoV-2 infection is not well understood.

Objective

To compare seroconversion in nonhospitalized children and adults with mild SARS-CoV-2 infection and identify factors that are associated with seroconversion.

Design, setting, and participants

This household cohort study of SARS-CoV-2 infection collected weekly nasopharyngeal and throat swabs and blood samples during the acute (median, 7 days for children and 12 days for adults [IQR, 4-13] days) and convalescent (median, 41 [IQR, 31-49] days) periods after polymerase chain reaction (PCR) diagnosis for analysis. Participants were recruited at The Royal Children's Hospital, Melbourne, Australia, from May 10 to October 28, 2020. Participants included patients who had a S

SUBMITTER: Toh ZQ 

PROVIDER: S-EPMC8908077 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature