New prognostic biomarker CMTM3 in low grade glioma and its immune infiltration.

ABSTRACT:

Background

The CKLF-like MARVEL transmembrane domain-containing 3 (CMTM3) is differentially expressed in a variety of tumors and closely related to tumor occurrence and progression. The expression of CMTM3 was significantly elevated in glioma compared with normal brain tissue, to explore the potential function of CMTM3 in the prognosis and immune infiltration of glioma has certain clinical significance.

Methods

The tumor data in this study were derived from the sequencing data of various tumors in The Cancer Genome Atlas (TCGA) database. Low-grade glioma (LGG) data in the TCGA database include sequencing and clinical data. Clinical data mainly include survival time, survival outcome, age, WHO classification and other information. Sequencing data for norm

SUBMITTER: Li S 

PROVIDER: S-EPMC8908177 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature