Ultrasound shows swollen joints are the better proxy for synovitis than tender joints in DMARD-naive early psoriatic arthritis.

ABSTRACT:

Objective

To evaluate the relationship between clinical examination/US synovitis in DMARD-naïve early PsA.

Methods

Eligible patients underwent matched clinical/US 44-joint assessment for tender and/or swollen joints (TJ/SJ) and US synovitis [grey scale (GS) ≥ 2 or power Doppler (PD) ≥ 1]. Statistical agreement between TJ/SJ, GS ≥ 2 and PD ≥ 1 was calculated by prevalence-adjusted and bias-adjusted κ (PABAK). To derive probabilities of GS ≥ 2/PD ≥ 1, mixed-effects logistic regression-modelled odds of US synovitis in TJ/SJ were conducted.

Results

In 155 patients, 5616 joints underwent clinical/US examination. Of these joints, 1039 of 5616 (18.5%) were tender, 550 of 5616 (9.8%) were swollen, 1144 of 5616 (20.4%) had GS ≥ 2, and 292 of 5616 (5.2%) had PD ≥ 1. GS ≥ 2 was

SUBMITTER: Dubash SR 

PROVIDER: S-EPMC8908782 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature