Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review.

ABSTRACT:

Objective

This study aimed to review evidence from randomized controlled trials (RCTs) to describe: 1) the active ingredients and desensitizing toothpaste brands; 2) the evaluation of these active ingredients over time, and 3) the fluoride and abrasive content in the formulations designed to treat dentin hypersensitivity (DH).

Methodology

In total, 138 RCTs and their tested toothpastes were included. Searches were updated up to August 19, 2021. Formulations, reported brands, active ingredients over time, and type of fluoride (ionizable or ionic fluoride) and abrasive (calcium or silica-based) were analyzed (PROSPERO #CRD42018086815).

Results

Our trials assessed 368 toothpaste formulations, including 34 placebo (9%), 98 control toothpastes with fluoride (27%), and 236

SUBMITTER: Martins CC 

PROVIDER: S-EPMC8908863 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature