Ontology highlight
ABSTRACT:
SUBMITTER: Brocco D
PROVIDER: S-EPMC8909146 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Brocco Davide D Simeone Pasquale P Buca Davide D Marino Pietro Di PD De Tursi Michele M Grassadonia Antonino A De Lellis Laura L Martino Maria Teresa MT Veschi Serena S Iezzi Manuela M De Fabritiis Simone S Marchisio Marco M Miscia Sebastiano S Cama Alessandro A Lanuti Paola P Tinari Nicola N
Cancers 20220307 5
Colorectal cancer (CRC) is one of the most incident and lethal malignancies worldwide. Recent treatment advances prolonged survival in patients with metastatic colorectal cancer (mCRC). However, there are still few biomarkers to guide clinical management and treatment selection in mCRC. In this study, we applied an optimized flow cytometry protocol for EV identification, enumeration, and subtyping in blood samples of 54 patients with mCRC and 48 age and sex-matched healthy controls (HCs). The ov ...[more]