Ontology highlight
ABSTRACT:
SUBMITTER: Schimke LF
PROVIDER: S-EPMC8909161 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Schimke Lena F LF Marques Alexandre H C AHC Baiocchi Gabriela Crispim GC de Souza Prado Caroline Aliane CA Fonseca Dennyson Leandro M DLM Freire Paula Paccielli PP Rodrigues Plaça Desirée D Salerno Filgueiras Igor I Coelho Salgado Ranieri R Jansen-Marques Gabriel G Rocha Oliveira Antonio Edson AE Peron Jean Pierre Schatzmann JPS Cabral-Miranda Gustavo G Barbuto José Alexandre Marzagão JAM Camara Niels Olsen Saraiva NOS Calich Vera Lúcia Garcia VLG Ochs Hans D HD Condino-Neto Antonio A Overmyer Katherine A KA Coon Joshua J JJ Balnis Joseph J Jaitovich Ariel A Schulte-Schrepping Jonas J Ulas Thomas T Schultze Joachim L JL Nakaya Helder I HI Jurisica Igor I Cabral-Marques Otávio O
Cells 20220301 5
Severe COVID-19 patients present a clinical and laboratory overlap with other hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH). However, the underlying mechanisms of these conditions remain to be explored. Here, we investigated the transcriptome of 1596 individuals, including patients with COVID-19 in comparison to healthy controls, other acute inflammatory states (HLH, multisystem inflammatory syndrome in children [MIS-C], Kawasaki disease [KD]), and different respi ...[more]