Therapeutic Potential of Certain Terpenoids as Anticancer Agents: A Scoping Review.

ABSTRACT: Cancer is a life-threatening disease and is considered to be among the leading causes of death worldwide. Chemoresistance, severe toxicity, relapse and metastasis are the major obstacles in cancer therapy. Therefore, introducing new therapeutic agents for cancer remains a priority to increase the range of effective treatments. Terpenoids, a large group of secondary metabolites, are derived from plant sources and are composed of several isoprene units. The high diversity of terpenoids has drawn attention to their potential anticancer and pharmacological activities. Some terpenoids exhibit an anticancer effect by triggering various stages of cancer progression, for example, suppressing the early stage of tumorigenesis via induction of cell cycle arrest, inhibiting cancer cell differentiation

SUBMITTER: Kamran S 

PROVIDER: S-EPMC8909202 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature