Efficacy and Safety of Bevacizumab-Combined Chemotherapy for Advanced and Recurrent Endometrial Cancer: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Bevacizumab-combined chemotherapy is a new regimen for advanced/recurrent endometrial cancer.

Aims

To evaluate the efficacy and safety of bevacizumab-combined chemotherapy in advanced/recurrent endometrial cancer.

Study design

Systematic review and meta-analysis.

Methods

Eligible studies were retrieved from Embase, PubMed, and Cochrane Library. The data of primary outcomes including progression-free survival and overall survival and secondary outcomes including overall survival, response rate, and adverse events (grade ≥2) were extracted, pooled, and used for the meta-analysis to compare the efficacy and safety of bevacizumab-combined chemotherapy with other treatments in patients with advanced/recurrent endometrial cancer.

Results

Notably, 2

SUBMITTER: Chen H 

PROVIDER: S-EPMC8909221 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature