Ontology highlight
ABSTRACT:
SUBMITTER: Amatu A
PROVIDER: S-EPMC8909235 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Amatu Alessio A Mauri Gianluca G Tosi Federica F Bencardino Katia K Bonazzina Erica E Gori Viviana V Ruggieri Lorenzo L Arena Sabrina S Bardelli Alberto A Marsoni Silvia S Siena Salvatore S Sartore-Bianchi Andrea A
Cancers 20220225 5
<h4>Background</h4>oxaliplatin with fluoropyrimidine is a "mainstay" regarding the upfront treatment of metastatic colorectal cancer (mCRC). In contrast, the efficacy and safety of oxaliplatin-based regimens in late-care settings have been poorly reported.<h4>Methods</h4>we identified a real-world mCRC patient cohort who were re-treated with oxaliplatin, and in which clinicopathological features were retrospectively analyzed to identify efficacy-predictive determinants (RETROX-CRC study).<h4>Res ...[more]