Association between Maternal Periodontitis and Development of Systematic Diseases in Offspring.

ABSTRACT: Periodontal disease (PD) is one of the most common oral conditions affecting both youths and adults. There are some research works suggesting a high incidence of PD in pregnant women. As an inflammatory disease of bacterial origin, PD may result in the activation of the pathways affecting the course and the pregnancy outcome. The authors, based on the literature review, try to answer the PICO question: Does maternal periodontitis (exposure) influence the incidence of complications rates in pregnancy and the development of systemic diseases in childhood and adult offspring (outcome) in the humans of any race (population) compared to the offspring of mothers with healthy periodontium (comparison)? The authors try to describe the molecular pathways and mechanisms of these interdependencies. T

SUBMITTER: Starzynska A 

PROVIDER: S-EPMC8910384 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature