Colchicine for Prevention of Atrial Fibrillation after Cardiac Surgery in the Early Postoperative Period.

ABSTRACT: Postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery. It has been proven to be associated with an increase in the incidence of early complications and mortality, an increase in the rate of hospital stay duration, and economic costs of their treatment. One of the pharmaceutical drugs recommended by the American College of Cardiology (ACC)/American Heart Association (AHA) for preventing POAF is colchicine (class IIB). However, the results of research on the efficacy and safety of colchicine are ambiguous and, consequently, require further study. Evaluating the efficacy of short-term colchicine administration in the prevention of POAF in patients after open-heart surgery. Double-blind, randomized, placebo-controlled clinical trial. The subjects were randomly as

SUBMITTER: Shvartz V 

PROVIDER: S-EPMC8911341 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature