Decellularized Avian Cartilage, a Promising Alternative for Human Cartilage Tissue Regeneration.

ABSTRACT: Articular cartilage defects, and subsequent degeneration, are prevalent and account for the poor quality of life of most elderly persons; they are also one of the main predisposing factors to osteoarthritis. Articular cartilage is an avascular tissue and, thus, has limited capacity for healing and self-repair. Damage to the articular cartilage by trauma or pathological causes is irreversible. Many approaches to repair cartilage have been attempted with some potential; however, there is no consensus on any ideal therapy. Tissue engineering holds promise as an approach to regenerate damaged cartilage. Since cell adhesion is a critical step in tissue engineering, providing a 3D microenvironment that recapitulates the cartilage tissue is vital to inducing cartilage regeneration. Decellularized

SUBMITTER: Ayariga JA 

PROVIDER: S-EPMC8911734 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature