New Halogen-Containing Drugs Approved by FDA in 2021: An Overview on Their Syntheses and Pharmaceutical Use.
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SUBMITTER: Benedetto Tiz D
PROVIDER: S-EPMC8912053 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
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New Halogen-Containing Drugs Approved by FDA in 2021: An Overview on Their Syntheses and Pharmaceutical Use.
Benedetto Tiz Davide D Bagnoli Luana L Rosati Ornelio O Marini Francesca F Sancineto Luca L Santi Claudio C
Molecules (Basel, Switzerland) 20220302 5
This review describes the recent Food and Drug Administration (FDA)-approved drugs (in the year 2021) containing at least one halogen atom (covalently bound). The structures proposed throughout this work are grouped according to their therapeutical use. Their synthesis is presented as well. The number of halogenated molecules that are reaching the market is regularly preserved, and 14 of the 50 molecules approved by the FDA in the last year contain halogens. This underlines the emergent role of ...[more]
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