Cortical and medullary oxygenation evaluation of kidneys with renal artery stenosis by BOLD-MRI.

ABSTRACT:

Aim

Blood oxygen level-dependent magnetic resonance imaging (BOLD-MRI) can measure deoxyhemoglobin content. This study aims to evaluate the capacity of BOLD-MRI, which is possible to evaluate the oxygenation state of kidneys with renal artery stenosis (RAS).

Materials and methods

We performed BOLD-MRI for 40 patients with RAS and for 30 healthy volunteers. We then performed post-scan processing and analysis of manually drawn regions of interest to determine R2* values (relaxation rates) for the renal cortex and medulla. We compared R2* values in patients with RAS with those in the control group, and also compared these values for subgroups with varying degrees of stenosis.

Results

Medulla R2* values were higher than cortex R2* values in the control group. There was no

SUBMITTER: Zhao L 

PROVIDER: S-EPMC8912187 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature