Incremental Doses of Nitrate-Rich Beetroot Juice Do Not Modify Cognitive Function and Cerebral Blood Flow in Overweight and Obese Older Adults: A 13-Week Pilot Randomised Clinical Trial.

ABSTRACT: Nitrate-rich food increases nitric oxide (NO) production and may have beneficial effects on vascular, metabolic, and brain function. This pilot study tested the effects of prolonged consumption of a range of doses of dietary nitrate (NO₃^-), provided as beetroot juice, on cognitive function and cerebral blood flow (CBF) in overweight and obese older participants. The study had a 13-week single-blind, randomised, parallel design, and 62 overweight and obese older participants (aged 60 to 75 years) received the following interventions: (1) high NO₃^- (2 × 70 mL beetroot juice/day) (2) medium NO₃^- (70 mL beetroot juice/day), (3) low NO₃^- (70 mL beetroot juice on alternate days), or (4) placebo (70 mL of NO

SUBMITTER: Babateen AM 

PROVIDER: S-EPMC8912345 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature