Chicory: Understanding the Effects and Effectors of This Functional Food.

ABSTRACT: Industrial chicory has been the subject of numerous studies, most of which provide clinical observations on its health effects. Whether it is the roasted root, the flour obtained from the roots or the different classes of molecules that enter into the composition of this plant, understanding the molecular mechanisms of action on the human organism remains incomplete. In this study, we were interested in three molecules or classes of molecules present in chicory root: fructose, chlorogenic acids, and sesquiterpene lactones. We conducted experiments on the murine model and performed a nutrigenomic analysis, a metabolic hormone assay and a gut microbiota analysis, associated with in vitro observations for different responses. We have highlighted a large number of effects of all these classes

SUBMITTER: Pouille CL 

PROVIDER: S-EPMC8912540 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature