Faecal Microbiota in Infants and Young Children with Functional Gastrointestinal Disorders: A Systematic Review.

ABSTRACT: Functional gastrointestinal disorders (FGIDs) refer to gastrointestinal tract issues that lack clear structural or biochemical causes. Their pathophysiology is still unclear, but gut microbiota alterations are thought to play an important role. This systematic review aimed to provide a comprehensive overview of the faecal microbiota of infants and young children with FGIDs compared to healthy controls. A systematic search and screening of the literature resulted in the inclusion of thirteen full texts. Most papers reported on infantile colic, only one studied functional constipation. Despite methodological limitations, data show alterations in microbial diversity, stability, and colonisation patterns in colicky infants compared to healthy controls. Several studies (eight) reported increase

SUBMITTER: Hofman D 

PROVIDER: S-EPMC8912645 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature