Maternal Zinc, Copper, and Selenium Intakes during Pregnancy and Congenital Heart Defects.

ABSTRACT: The effects of zinc, copper, and selenium on human congenital heart defects (CHDs) remain unclear. This study aimed to investigate the associations of the maternal total, dietary, and supplemental intakes of zinc, copper, and selenium during pregnancy with CHDs. A hospital-based case-control study was performed, including 474 cases and 948 controls in Northwest China. Eligible participants waiting for delivery were interviewed to report their diets and characteristics in pregnancy. Mixed logistic regression was adopted to examine associations and interactions between maternal intakes and CHDs. Higher total intakes of zinc, selenium, zinc to copper ratio, and selenium to copper ratio during pregnancy were associated with lower risks of total CHDs and the subtypes, and the tests for trend we

SUBMITTER: Yang J 

PROVIDER: S-EPMC8912688 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature