Murine allele and transgene symbols: ensuring unique, concise, and informative nomenclature.

ABSTRACT: In addition to naturally occurring sequence variation and spontaneous mutations, a wide array of technologies exist for modifying the mouse genome. Standardized nomenclature, including allele, transgene, and other mutation nomenclature, as well as persistent unique identifiers (PUID) are critical for effective scientific communication, comparison of results, and integration of data into knowledgebases such as Mouse Genome Informatics (MGI), Alliance for Genome Resources, and International Mouse Strain Resource (IMSR). As well as being the authoritative source for mouse gene, allele, and strain nomenclature, MGI integrates published and unpublished genomic, phenotypic, and expression data while linking to other online resources for a complete view of the mouse as a valuable model organism.

SUBMITTER: Perry MN 

PROVIDER: S-EPMC8913455 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature