Rapid selection response to ethanol in Saccharomyces eubayanus emulates the domestication process under brewing conditions.

ABSTRACT: Although the typical genomic and phenotypic changes that characterize the evolution of organisms under the human domestication syndrome represent textbook examples of rapid evolution, the molecular processes that underpin such changes are still poorly understood. Domesticated yeasts for brewing, where short generation times and large phenotypic and genomic plasticity were attained in a few generations under selection, are prime examples. To experimentally emulate the lager yeast domestication process, we created a genetically complex (panmictic) artificial population of multiple Saccharomyces eubayanus genotypes, one of the parents of lager yeast. Then, we imposed a constant selection regime under a high ethanol concentration in 10 replicated populations during 260 generations (6 months) a

SUBMITTER: Mardones W 

PROVIDER: S-EPMC8913853 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature