Transcriptome profiling of the liver among the prenatal and postnatal stages in chickens.

ABSTRACT: The liver is an important organ that has pivotal functions in the synthesis of several vital proteins, the metabolism of various biologically useful materials, the detoxification of toxic substances, and immune defense. Most liver functions are not mature at a young age and many changes happen during postnatal liver development, which lead to differential functions of the liver at different developmental stages. However, the transcriptome details of what changes occur in the liver after birth and the molecular mechanisms for the regulation of the developmental process are not clearly known in chickens. Here, we used RNA-sequencing to analyze the transcriptome of chicken liver from the prenatal (at an embryonic day of 13) to the postnatal stages (at 5 wk and 42 wk of age). A total of approx

SUBMITTER: Xu E 

PROVIDER: S-EPMC8913967 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature