Association Between Depression and Severity of Dry Eye Symptoms, Signs, and Inflammatory Markers in the DREAM Study.

ABSTRACT:

Importance

Depression is more prevalent in patients with dry eye disease (DED) than in the general population; however, the association between severity of DED and depression needs further evaluation.

Objective

To investigate the association between depression and severity of DED symptoms and signs, including inflammatory markers.

Design, setting, and participants

Secondary cross-sectional and longitudinal analysis performed in April to December 2020 of data from Dry Eye Assessment and Management (DREAM) study, a randomized clinical trial from October 2014 to July 2016 including patients with moderate to severe symptoms and signs of DED. Enrolled from 27 ophthalmology and optometry centers, both academic and private, in 17 US states, 535 patients were followed up for

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC8914873 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature