Evaluation of Antibody Response to SARS-CoV-2 mRNA-1273 Vaccination in Patients With Cancer in Florida.

ABSTRACT:

Importance

Patients with cancer experience high rates of morbidity and mortality after SARS-CoV-2 infection. Immune response to mRNA-1273 vaccination across multiple cancer types and treatments remains to be established.

Objective

To quantitate antibody responses after mRNA-1273 vaccination among patients with solid tumors and hematologic cancer and to assess clinical and treatment factors associated with vaccine response.

Design, setting, and participants

This cohort study included patients with cancer who were aged 18 years or older, spoke English or Spanish, had received their first mRNA-1273 dose between January 12 and 25, 2021, and agreed to blood tests before and after vaccination.

Exposures

Receipt of 1 and 2 mRNA-1273 SARS-CoV-2 vaccine doses.

Main o

SUBMITTER: Giuliano AR 

PROVIDER: S-EPMC8914884 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature