Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop.

ABSTRACT:

Objectives

The objective of this study was to develop a core outcome set (COS) for use in future clinical trials in bronchiolitis. We wanted to find out which outcomes are important to healthcare professionals (HCPs) and to parents and which outcomes should be prioritised for use in future clinical trials.

Design and setting

The study used a systematic review, workshops and interviews, a Delphi survey and a final consensus workshop.

Results

Thirteen parents and 45 HCPs took part in 5 workshops; 15 other parents were also separately interviewed. Fifty-six items were identified from the systematic review, workshops and interviews. Rounds one and two of the Delphi survey involved 299 and 194 participants, respectively. Sixteen outcomes met the criteria for inclusion with

SUBMITTER: Rosala-Hallas A 

PROVIDER: S-EPMC8915376 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature