Testing and treatment for latent tuberculosis infection in people living with HIV and substance dependence: a prospective cohort study.

ABSTRACT:

Objective

To quantify the proportion of people living with HIV (PLWH) with other tuberculosis (TB) risk factors that completed the latent tuberculosis infection (LTBI) care cascade and describe factors associated with attrition. The care cascade was defined as follows: (1) receipt of an LTBI test and result, (2) initiation of LTBI treatment and (3) completion of LTBI treatment.

Design

Prospective cohort study.

Setting

Reactivation of LTBI remains a large source of active TB disease in the USA. PLWH and those who use substances are at greater risk and are harder to engage and retain in care.

Participants

Participants enrolled in a Boston cohort of PLWH from 2012 to 2014.

Primary and secondary outcome measures

Our primary outcome was the number and proport

SUBMITTER: Runels T 

PROVIDER: S-EPMC8915380 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature