Predicting the course of asthma from childhood until early adulthood.

ABSTRACT:

Purpose of review

To communicate recent insights about the natural history of childhood asthma, with a focus on prediction of persistence and remission of childhood asthma, up to early adulthood.

Recent findings

Lung function around the age of 8-9 years is the strongest predictor: obstructive lung function predicts asthma persistence up to early adulthood, whereas normal lung function predicts remission. The ability to predict asthma remission improves when lung function is combined with blood eosinophil levels and degree of bronchial hyperresponsiveness. Interventions, such as inhaled corticosteroids and immunotherapy do not appear to alter the course of asthma. Epigenetic studies have revealed potential novel biomarkers of asthma remission, such as micro-RNA patterns in bl

SUBMITTER: Koefoed HJL 

PROVIDER: S-EPMC8915994 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature