Association of Different Definitions of Intradialytic Hypertension With Long-Term Mortality in Hemodialysis.

ABSTRACT:

Background

Hypertension is common in hemodialysis patients. A subset of patients experience systolic blood pressure increases from prehemodialysis to posthemodialysis (intradialytic hypertension), which are associated with adverse outcomes. However, little consensus exists on an evidence-based definition.

Methods

In 3198 hemodialysis patients, Cox models were fit to examine the association of various definitions of intradialytic hypertension (≥30% of baseline sessions with an increase in prehemodialysis to posthemodialysis systolic blood pressure of (1) ≥0 mm Hg [Hyper0]; (2) ≥10 mm Hg [Hyper10], or (3) ≥20 mm Hg increase [Hyper20]) with all-cause mortality. Effect modification was assessed using interaction terms according to prespecified variables.

Results

At baseli

SUBMITTER: Singh AT 

PROVIDER: S-EPMC8916991 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature