Large scale validation of an early-age eye-tracking biomarker of an autism spectrum disorder subtype.

ABSTRACT: Few clinically validated biomarkers of ASD exist which can rapidly, accurately, and objectively identify autism during the first years of life and be used to support optimized treatment outcomes and advances in precision medicine. As such, the goal of the present study was to leverage both simple and computationally-advanced approaches to validate an eye-tracking measure of social attention preference, the GeoPref Test, among 1,863 ASD, delayed, or typical toddlers (12-48 months) referred from the community or general population via a primary care universal screening program. Toddlers participated in diagnostic and psychometric evaluations and the GeoPref Test: a 1-min movie containing side-by-side dynamic social and geometric images. Following testing, diagnosis was denoted as ASD, ASD fe

SUBMITTER: Wen TH 

PROVIDER: S-EPMC8917231 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature