Survival and Surgical Approach among Women with Advanced Ovarian Cancer Treated with Neoadjuvant Chemotherapy.

ABSTRACT:

Study objective

To evaluate the effect of surgical approach on overall survival (OS) for women with advanced, epithelial ovarian cancer (EOC) after neoadjuvant chemotherapy (NACT) and determine the sociodemographic and clinical factors associated with surgical approach.

Design

The primary exposure was surgical approach to interval cytoreduction, minimally invasive versus open, and was evaluated by intention to treat. Primary outcome was OS. Associations were examined using Chi-squared tests, Wilcoxon rank sum tests, and multivariate logistic regression. Survival analysis was performed with Kaplan-Meier methods and Cox proportional hazards.

Setting

The National Cander Database was used to identify eligible patients.

Patients

Women diagnosed with stage IIIC/IV EO

SUBMITTER: Persenaire C 

PROVIDER: S-EPMC8918010 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature